Two znf-ubp domains in isopeptidase t usp5

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WebMar 24, 2006 · Two ZnF-UBP domains in isopeptidase T (USP5). G. Avvakumov, J. Walker, +8 authors S. Dhe-Paganon; Biology, Chemistry. Biochemistry. 2012; TLDR. Findings show … WebTwo ZnF-UBP Domains in Isopeptidase T (USP5) [2015] Avvakumov, George V.; Walker John R.author; Xue Shengauthor; Allali-Hassani Abdellahauthor; et al. Access the full text Link; …

The ZnF UBP domain is a novel ubiquitin‐binding domain that …

WebJan 31, 2024 · Wilkinson KD et al. (2012) Two ZnF-UBP domains in. isopeptidase T (USP5). Biochemistry 51, 1188 ... WebThe UBP-type zinc finger domain crystallizes as a dimer linked by a disulfide bond between the Cys-195 residues of both molecules, ... Isopeptidase T; Ubiquitin thioesterase 5; Ubiquitin-specific-processing protease 5; Gene names. Name. USP5. Synonyms. ... SM00165 UBA 2 hits; SM00290 ZnF_UBP 1 hit; SUPFAM. SSF54001 Cysteine proteinases 1 hit; building a motor bicycle

Deubiquitylases USP5 and USP13 are recruited to and regulate …

WebUSP5 uses multiple zinc fluoride (ZnF)-ubiquitin binding protein (UBP) domains for substrate targeting and core catalytic function. p53 is selectively stabilized because the unanchored … WebThe ZnF-UBP domain (aa 163-291) selectively interacts with an unmodified C-terminus of poly-Ubiquitin chains and induces a conformational change that prevents Isopeptidase … WebFeb 14, 2012 · Structurally, USP5 is constituted by two ZnF-UBP domains [42], a catalytic USP domain and two inserted UBA domains [22]. All the four Ub-binding domains … building a motorcycle engine

Author: "Fang, Xianyang" - PubAg Search Results

Human Gene USP5 (ENST00000389231.9) from GENCODE V43

WebFeb 2, 2015 · The BUZ/Znf-UBP domain is a distinct ubiquitin-binding module found in the cytoplasmic deacetylase HDAC6, the E3 ubiquitin ligase BRAP2/IMP, and a subfamily of deubiquitinating enzymes. WebTwo ZnF-UBP domains in isopeptidase T (USP5) Biochemistry Feb 2012 Other authors. The crystal structure of the N-terminal 15 heptads of smooth muscle myosin rod offers insights into the inhibited state of myosin Biophysical Journal Jan 2010 Other authors. Crystal ... crowe horwath dublinWebApr 4, 2006 · Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin. Released: 04 Apr 2006. DOI: … crowe horwath consulting salary

"WebNov 1, 2003 · Two ZnF-UBP domains in isopeptidase T (USP5). 18: 28933784: 2024: Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma … " - Two znf-ubp domains in isopeptidase t usp5

Two znf-ubp domains in isopeptidase t usp5

The structure of the deubiquitinase USP15 reveals a misaligned ...

WebDec 1, 2024 · Non-UBP domains Function Reference; 1: UBP1 (AT2G32780) Zf-UBP: canavanine resistance: Yan et al. (2000) UBP2 (AT1G04860) Zf-UBP: ... Two ZnF-UBP domains in isopeptidase T (USP5) Biochemistry, 51 (2012), pp. 1188-1198. CrossRef View in Scopus Google Scholar. Bender and Snedden, 2013. WebMar 28, 2014 · Two ZnF-UBP Domains in Isopeptidase T (USP5) journal, February 2012. Avvakumov, George V.; Walker, John R.; Xue, Sheng; Biochemistry, Vol. 51 ... The crystal …

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WebJul 1, 2024 · There are at least four ubiquitin-binding sites in USP5 (Fig. 2 c and 2d), S1′, S1, S2, and S3, which are located in the ZnF-UBP, UBP, UBA2, and UBA1 domains, … WebHuman Gene USP5 (uc001qri.4) Description: Homo sapiens ubiquitin specific peptidase 5 (isopeptidase T) (USP5), transcript variant 1, mRNA. RefSeq Summary (NM_001098536): Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin …

WebUbiquitin specific peptidase 5 is an enzyme that in humans is encoded by the USP5 gene. Interactions. USP5 has been shown to interact with TADA3L. References Further reading. … WebOct 1, 2024 · The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin journal, March 2006. Reyes-Turcu, Francisca E.; Horton, John R.; ... Two ZnF-UBP Domains in Isopeptidase T (USP5) journal, February 2012. Avvakumov, George V.; Walker, John R.; Xue, Sheng;

WebOct 3, 1995 · Two ZnF-UBP Domains in Isopeptidase T (USP5). Biochemistry 2012, 51 (6) , ... Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of … WebTwo ZnF-UBP Domains in Isopeptidase T (USP5) Human ubiquitin-specific cysteine protease 5 (USP5, also known as ISOT and isopeptidase T), an 835-residue multidomain …

WebFeb 14, 2012 · 2 Views 1 Download. Keywords: Science & Technology; Life Sciences & Biomedicine; Biochemistry ... PROTEINS; RECOGNITION; RESOLUTION; SYSTEM; Two ZnF …

WebThe UBP-type zinc finger domain is found only in a small subfamily of ubiquitin C-terminal hydrolases (deubiquitinases or UBP) [ (PUBMED:9759494) (PUBMED:9409543) ], All … crowe horwath first trust llp pcaobWebA late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]. Gencode Transcript ... building a motorcycle frame jigWebFeb 23, 2015 · Avvakumov GV, Walker JR, Xue S, lali-Hassani A, Asinas A, Nair UB, Fang X, Zuo X, Wang YX, Wilkinson KD, Dhe-Paganon S Two ZnF-UBP domains in isopeptidase T (USP5) BIOCHEMISTRY 51 (6):1188-1198 Feb 14 2012. Datta SA, Zuo X, … crowe horwath dubai