Ctsh protein
WebJan 30, 2024 · Another type 1 diabetes susceptibility gene, Cathepsin H (CTSH) [36, 37], is a lysosomal cysteine protease that is crucial for lysosomal protein degradation. Importantly, the CTSH susceptibility allele is associated with faster disease progression in newly diagnosed diabetes and reduced beta cell function in healthy humans . WebFurthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2 e,i,j). From this perspective, we found a novel ...
Ctsh protein
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WebMar 9, 2024 · Furthermore, the up-regulation of the CTSH protein in HepG2 cells after IR gave us a definitive answer to explain the phenomenon that the HepG2 cell was more resistant to radiation than the MHCC97H cell, in which the CTSH expression did not increase as significantly as in the HepG2 cell (Figure 2e,i,j). From this perspective, we … WebNM_004390.5(CTSH):c.296C>T (p.Pro99Leu) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Nov 29, 2024) Review status: 1 star out of maximum of 4 stars
WebNM_004390.5(CTSH):c.20T>C (p.Leu7Pro) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Mar 23, 2024) Review status: 1 star out of maximum of 4 stars WebCTSH. The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide …
WebCTSH INFORMATION. Proteini. Full gene name according to HGNC. Cathepsin H. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) Protein classi. Assigned HPA … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in amygdala … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in pancreas … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in midbrain tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in rectum tissue. … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in thyroid gland … GTEX-XYKS-2726-SM-4E3IC: 60-69 years, female: 93.2: GTEX-13OVL-0326-SM … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in fallopian tube … Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in skin tissue. … Smooth Muscle - CTSH protein expression summary - The Human Protein Atlas Expression of CTSH (ACC-4, ACC-5, ACC4, ACC5, CPSB) in stomach tissue. … WebCTSH; cathepsin H; Description From CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal …
WebThe cytoskeletal protein talin, an actin- and β-integrin tail-binding protein, plays an important role in cell migration by promoting integrin activation and focal adhesion formation. Here, we show that talin is a substrate for cathepsin H (CtsH), a lysosomal cysteine protease with a strong aminopeptidase activity. Purified active CtsH sequentially cleaved …
WebThe protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked … dialysis treatment explainedWebCathepsin H (CTSH) is a type 1 diabetes (T1D) risk gene; large-scale genetic and epidemiological studies found that T1D genetic risk correlates with high CTSH … circeo hiking tripWebConsistent with extensive gene/protein characterization data. Consistent with extensive gene/protein characterization data. RNA consistency i High consistency between antibody staining and RNA expression data. High consistency between antibody staining and RNA expression data. ... CTSH-201. CTSH-207. CTSH-218. CTSH-232. CTSH-233. CTSH … circe overviewWebInterestingly, the CTSH protein expression data support the clinical observation that the TT genotype differs from the CC and CT genotypes. The lack of association between CTSH … dialysis treatment durationWebMar 11, 2024 · Cathepsin B (CTSB) is an exclusive multifunctional protein of cysteine protease family in that it has an additional pH sensitive occluding loop which allows it to … circe other namesWebFrom CBI Gene: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of … dialysis treatment cost in usaWebView mouse Ctsh Chr9:89936320-89958148 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression dialysis treatment for dogs