WebMar 14, 2024 · They can be life-threatening at times. Drug-induced hematologic disorders can affect any type of cell line. The various types of drug-induced blood dyscrasias presented are, immune and non-immune hemolytic anemia, aplastic anemia, megaloblastic anemia, sideroblastic anemia, methemoglobinemia, pure red cell aplasia, immune … WebApr 24, 2009 · Abstract Reports of 576 published and unpublished cases of blood dyscrasias attributed to chloramphenicol have been studied. Pancytopenia (aplastic …
Blood dyscrasias attributed to chloramphenicol
WebDec 30, 1986 · Abstract. The case reports presented so far, concerning a possible causative relationship between the ophthalmological use of chloramphenicol (O-CAP) and blood … WebJan 1, 1999 · The seventh patient had a record of ophthalmic chloramphenicol use in 1983 without any adverse incident, and later in the same year was given systemic chloramphenicol for typhoid fever, and subsequently developed a blood dyscrasia from which he recovered completely following cessation of systemic chloramphenicol. option photo excel
Chloramphenicol-Associated Blood Dyscrasias - JAMA
WebJun 16, 2024 · Chloramphenicol eye and ear preparations can be used with caution during breastfeeding. However, they should not be used in individuals where there is a past or family history of blood dyscrasias. Fusidic acid or gentamicin preparations would be preferred, if clinically appropriate. Milk levels WebChloramphenicol may cause Gray syndrome and serious, fatal blood dyscrasias. Gray syndrome occurs in pre-mature infants and neonates. It involves abdominal distention, pallid cyanosis, and vasomotor collapse leading to death. Blood dyscrasias are reductions in blood cells leading to aplastic anemia, thrombocytopenia, and granulocytopenia. WebChloramphenicol is a broad-spectrum antimicrobial agent. It acts by inhibiting protein synthesis. Its high lipid solubility results in rapid absorption, a large volume of … option picks